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What Are Lip Filler Side Effects? Risks, Safety & Aftercare

  • Dr. Shehnaz Quasim
  • Sep 26
  • 7 min read

Updated: 24 minutes ago

Lip filler side effects are the changes you may notice after injections that add volume or shape to the lips, most commonly with hyaluronic acid gel. Because fillers are a medical treatment, your body can react in short‑term ways — swelling, bruising and tenderness — and, rarely, in reactions that need urgent attention, such as infection or reduced blood flow. Knowing what’s normal, what isn’t, and how to respond makes the process safer and less stressful.


In this guide, we break down how lip fillers work, the most common after effects, the uncommon but important risks and red‑flag symptoms, and what the evidence says about long‑term effects. You’ll find practical steps to reduce your risk before your appointment, clear aftercare advice to minimise side effects, and tips for handling lumps, cold sores or filler migration. We’ll also cover UK safety and regulation, how long results last, whether fillers can be reversed, and key questions to ask at consultation.


How lip fillers work and what’s in them


Most modern lip fillers are soft hyaluronic acid (HA) gels injected just under the skin to restore or add volume and refine shape. Placed with a very fine needle in precise points of the lips, the gel sits in the tissue to support and contour; results are temporary and can be reversed with hyaluronidase if needed.


Many HA fillers contain a little lidocaine for comfort, and clinicians may apply topical anaesthetic. Treatments commonly use about 1 mL of filler with shallow placement of a few millimetres. Understanding this helps explain normal lip filler side effects.


Common, short-term side effects (and what’s normal)


Right after treatment, the most common lip filler side effects are swelling, tenderness, redness and small bruises at the injection points. Swelling usually peaks in the first 24–48 hours and settles within a week; discomfort is mild and typically eases within 12–24 hours. Small spots of bleeding and temporary numbness from the anaesthetic can also occur. If you’re prone to cold sores, reactivation is possible.


  • Swelling: typically 24–48 hours; may last up to a week.

  • Bruising: fades over a few days; sometimes up to a week.

  • Redness, tenderness or mild itching: improves within a couple of days.

  • Pinpoint bleeding or dot‑like marks: should stop quickly and fade within 24–48 hours.


To calm these, ice in 10‑minute bursts, avoid lipstick, touching, straws, exercise and alcohol for 24 hours, and keep well hydrated.


Less common but serious risks to be aware of


Serious lip filler side effects are uncommon — especially with an experienced medical injector using approved hyaluronic acid fillers — but they do happen and deserve your attention. Recognising them early protects your lips and, in rare cases, your sight and overall health.


  • Vascular compromise (blocked blood flow): filler entering or compressing a vessel can cause skin blanching, severe pain and, without urgent treatment, tissue loss.

  • Intravascular injection to critical vessels: very rare but can lead to skin necrosis, stroke or blindness.

  • Infection: worsening redness, heat, pain, pus or fever; can progress to cellulitis or abscess and needs prompt antibiotics.

  • Nodules or granulomas: firm or raised bumps weeks to months later; may require medication or dissolving.

  • Allergic reactions: uncommon with HA, but reactions to filler components or lidocaine can cause swelling, rash or itching.

  • Ulceration, scarring or stiffening: usually linked to significant inflammation or poor healing.

  • Filler migration or asymmetry: unintended movement or unevenness that may need correction.


Knowing the warning signs — and acting quickly — is key. Next, what to watch for and when to seek urgent help.


Red flag symptoms: when to seek urgent help


Most lip filler side effects are mild, but a small set of symptoms demand urgent attention. Act fast — the sooner you’re seen, the better the outcome. Contact your injector or an urgent care service; for eye symptoms or breathing problems, go straight to A&E or call 999.


  • Vision changes or loss of vision: this can signal filler in a blood vessel.

  • Severe, worsening pain with marked discolouration (pale, blue or mottled) or blisters/ulcers.

  • Signs of infection: spreading redness, heat, increasing swelling, pus or fever.

  • Allergic reaction: rash/hives, facial or throat swelling, wheeze or breathing difficulty.

  • Severe or prolonged swelling/bruising that persists beyond 7–10 days.

  • Painful, hot or enlarging lumps, or new firm nodules.


Early treatment may include antibiotics for infection or dissolving HA filler with hyaluronidase for suspected vascular compromise.


Long-term side effects and what the evidence says


Most evidence shows hyaluronic acid lip fillers are temporary (usually 12–18 months) and, when performed by trained clinicians, long‑term side effects are uncommon. Still, delayed reactions do happen: firm nodules or granulomas weeks to years later; site inflammation after illnesses, vaccinations or dental work; persistent asymmetry or migration; and, less often, scarring or stiffness after significant inflammation.


Poor technique and non‑medical injectors increase the risk — in extreme cases lips can be permanently stretched or tissue can die; fortunately HA‑related issues like lumps or migration can often be corrected, including dissolving with hyaluronidase after assessment. Always seek assessment early.


Who should avoid lip fillers or delay treatment


Not everyone is a good candidate for lip fillers. For safety, some people should avoid or postpone treatment to reduce the risk of lip filler side effects. Share your medical history and medicines so your clinician can tailor care. If any of the following apply, you may be asked to wait or seek GP clearance.


  • Under 21–22 (product‑dependent): Not approved for minors.

  • Pregnant: Defer until after pregnancy.

  • Active oral infection or cold sore history: Pause and inform your clinician.

  • Unwell/recent vaccination or dental work: Delay treatment.

  • Diabetes, lupus or clotting disorders: Seek medical clearance.

  • Severe allergies or lidocaine allergy: Requires risk assessment.

  • Body dysmorphic concerns/unrealistic expectations: Consider support first.


How to reduce your risk before your appointment


Good preparation lowers the chance of lip filler side effects and helps you recover on time. The goal is simple: choose the right clinician, time your treatment well, and share the information they need to keep you safe. Use this pre‑appointment checklist.


  • Pick a medical injector: Choose a licensed clinician using approved HA fillers; avoid salons, self‑injection or needle‑free pens.

  • Share your full history: Include conditions, allergies (especially lidocaine/BLT), and all medicines and supplements; never stop meds without advice.

  • Flag cold sores: Reactivation can happen; tell your clinician so they can plan to reduce risk.

  • Postpone if unwell: Delay if you have an active oral infection, canker sore or cold sore.

  • Time it wisely: Space treatment from recent vaccinations or dental work, and wait until fully recovered from illness.

  • Plan your diary: Book at least two weeks before big events to allow swelling/bruising to settle.

  • Verify the product and plan: Ask which filler is used and where it’ll be placed, read patient information, check sealed/labelled syringes, and confirm access to hyaluronidase and follow‑up care.


Aftercare tips to minimise side effects


The first 48 hours shape your recovery. Simple habits can significantly reduce lip filler side effects like swelling and bruising, lower infection risk, and help your results settle evenly and naturally. Follow your clinician’s instructions closely and use the steps below in the hours and days after treatment. Plan a quiet day to give your lips a calm start.


  • Ice 10 minutes at a time to reduce swelling and discomfort.

  • No lip products for 24 hours (lipstick, liner or balm).

  • Hands off: Don’t touch, massage or pucker; no kissing or straws.

  • Eat/brush with care: Wait until numbness wears off; avoid messy foods.

  • For 24 hours avoid: vigorous exercise, smoking and alcohol.

  • Monitor: If redness spreads, heat, pus or fever develop, contact your clinician; keep your two‑week review.


What to do if you get lumps, cold sores or filler migration


Small bumps, cold sores or a hint of filler movement can happen after lip fillers. Most are fixable, but timing matters — don’t try to self‑correct. Contact your injector promptly, keep photos, and use your two‑week review to reassess once early swelling has settled.


  • Lumps or bumps: Minor unevenness usually settles in week one as swelling/bruising fade. Don’t self‑massage. If a lump is painful, hot, enlarging or still present at review, book assessment — HA filler can often be smoothed or dissolved (hyaluronidase).

  • Cold sores: Reactivation can occur (tingling, burning, blisters). Tell your clinician and postpone further injections. Keep it clean, avoid touching and kissing, and follow their treatment advice. Escalate if pain, spreading redness or fever develop.

  • Migration or asymmetry: Judge shape once swelling settles (by your two‑week check). Options are observation, small balancing treatment, or dissolving misplaced HA before re‑treating. Use an experienced medical injector to correct and prevent migration.


Safety and regulation in the UK


In the UK, safety comes down to who treats you, where, and what they use. Treat lip fillers as a medical procedure in a clinical setting — not a beauty salon or at home. Follow the safeguards below to lower the risk of lip filler side effects and ensure rapid help if needed.


  • Choose a medical injector: Verify training and experience in dermal fillers.

  • Check the product: Sealed, properly labelled syringes of hyaluronic acid; never buy fillers sold to the public.

  • Avoid needle‑free pens and DIY kits: Do not self‑inject.

  • Confirm an emergency plan: On‑site hyaluronidase and clear escalation pathways.

  • Expect proper process: Consultation, consent, records and a planned follow‑up review.


How long results last and whether fillers can be reversed


Results from hyaluronic acid lip fillers are temporary. Most people enjoy their outcome for about 12–18 months, though this varies with age and metabolism, and some notice fading sooner. To maintain your look, periodic top‑ups are normal.


  • Reversible when needed: HA fillers can be dissolved with hyaluronidase by a trained clinician if you’re unhappy with the result.

  • Not all fillers are reversible: Non‑HA products aren’t easily dissolved; removal may require other procedures.

  • Dissolving is a treatment: It may take more than one session and carries its own risks, so it should be performed in a clinical setting.


Questions to ask at your consultation


Use your consultation to confirm safety, suitability and expectations. Ask targeted questions about product, risks and aftercare.


  • Experience: How many lip filler cases do you perform?

  • Product choice: Which HA brand, and is it reversible?

  • Risks and emergencies: What risks apply to me; do you stock hyaluronidase and what's your plan?

  • Anaesthetic: What will you use; options if lidocaine‑sensitive?

  • Aftercare and review: What pre/aftercare and follow‑up timetable should I expect?

  • Cold sores: How will you prevent and treat them?

  • Realistic results: What outcome is achievable; can I see similar cases?

  • Costs and policies: Fees, touch‑ups and dissolving policy?


Conclusion section


Lip fillers are a medical treatment, and like any procedure they come with expected, short‑lived effects and a small chance of serious complications. You now know what fillers are made of, what’s normal in the first week, the red‑flag symptoms that need urgent help, who should pause or avoid treatment, and the practical steps that reduce risk and speed recovery. We’ve also covered managing lumps, cold sores and migration, UK safety basics, how long results last and when dissolving is appropriate.


If you’re considering treatment — or have questions about side effects — book a no‑pressure consultation with a medically led team you trust. At Wigmore Smiles & Aesthetics in Luton, we offer clear advice, tailored plans, meticulous aftercare and a welcoming approach for nervous patients, with flexible 0% finance available. Get safe, natural‑looking results with continuity of care from consultation to review.

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